Erythema multiforme major is the term used to describe em with severe mucosal involvement and. If you continue browsing the site, you agree to the use of cookies on this website. Eritema multiforme wikipedia, a enciclopedia livre. Em is clinically characterized by a minor form and a major form. Pdf erythema multiforme is an eritfma or chronic inflammatory mucocutaneous manifestation of variable morphological expression. Iphoto fotobuch in pdf symptoms include fever, malaise, sore throat, cough, vomiting, diarrhea, arthralgia, and myalgia. Steven johnson syndrome sjs, toxic epidermal necrolysis ten and erythema multiforme for usmle duration. This study revises the em minor characteristics according to the. Erythema multiforme is associated with an acute onset. Retrieved 28 november erythema multiforme em erythema multiforme minor of the hands note the blanching centers of the lesion specialty dermatology erythema multiforme em is a skin condition of unknown cause.
It is an uncommon disorder, with peak incidence in the second and third decades of life. Pdf erythema multiforme is an acute or chronic inflammatory mucocutaneous manifestation of variable morphological expression. This means that the body is sensitive to something that causes the skin and mucous membranes to react. Erythema nodosum usually is idiopathic,2,4,7 but there are many possible causes table 2. Physicians should consider all possible etiologies of erythema nodosum and take a comprehensive history.
Histologically, each shows varying degrees of dermal and epidermal inflammation and injury. Las formas leves normalmente no requieren tratamiento. Theres also a much more severe and lifethreatening form of em that may affect the mouth, eyes, and even genitals. Pdf erythema multiforme em is an acute, selfhealing inflammatory mucocutaneous disorder which presents with diverse spectrum of cutaneous lesions. Erythema multiforme em is an acute, immunemediated condition characterized by the appearance of distinctive targetlike lesions on the skin picture 1ah. Eritema multiforme manifestaciones oculares provisu. It presents a diagnostic dilemma because the oral cavity has the ability to produce varied manifestations. Erythema anulare centrifugum eac, also known as deep gyrate erythema, erythema perstans, palpable migrating erythema and superficial gyrate erythema. The minor form is additionally subdivided into papular and vesiculobullous variants, and all three have been considered a continuum of the same process. Erythema multiforme minor erythema multiforme major stevensjohnson syndrometoxic epidermal polimoorfo panniculitis erythema nodosum acute generalized exanthematous pustulosis. Erythema multiforme minor typical target lesions, raised atypical target lesions, minimal mucous membrane involvement and, when present, at only 1 site most commonly the mouth.
Its typically mild and will resolve after a few weeks. Erythema multiforme is usually a reaction of the skin and mucous membranes that occurs suddenly. Erythema multiforme em is a skin condition of unknown cause. Toxic epidermal necrolysis, manifested by widespread epidermal desquamation, is the. Mucosal changes, if present, consist initially of redness of the lips and inside the cheek.
Episodic angioedema with eosinophilia hereditary angioedema. Sometimes blisters develop and quickly break to form erosions and ulcers. These lesions are often accompanied by erosions or bullae involving the oral, genital, andor ocular mucosae picture 2ac. Recently, erythema multiforme has been classified as minor, major, stevensjohnson syndrome or toxic epidermal necrolysis, where erythema multiforme minor is the mildest type of lesion and toxic epidermal necrolysis the most severe2,3 table 1. Retrieved 28 november erythema multiforme minor erythema multiforme major stevensjohnson syndrometoxic epidermal necrolysis panniculitis erythema nodosum acute generalized exanthematous pustulosis. It appears as a symmetrical rash and may include the mucous membrane lesions.
Erythema multiforme is a reactive mucocutaneous disorder in a disease spectrum that comprises a selflimited, mild, exanthematic, cutaneous variant with minimal oral involvement em minor to a. Two types, one mild to moderate and one severe, are recognized erythema multiforme minor and erythema multiforme major. It consists of a skin rash that involve no more than one mucosal surface. Erythema multiforme em is an interesting dermatologic disease which has oral manifestations. Em is a rash thats usually caused by an infection or medication. It occurs predominantly in young adults, is slightly more common in females, and the incidence is somewhere between 0. Erythema multiforme em has been divided into a minor simplex form and a major bullous form. Erythema multiforme minor presents as a bulging, rashlike lesion that is red, pink, purple, or brown. A abordagem dos aspectos atuais do eritema multiforme e a. Erythema multiforme may be a mild condition erythema multiforme minor, or it may be a severe, possibly lifethreatening condition erythema multiforme major or stevensjohnson syndrome. Revision y puesta al dia gavaldaesteve, carmen erythema multiforme. Em with mucosal involvement is known as erythema multiforme major, and without mucosal disease it is referred to as erythema multiforme minor. It is usually circular, less than 3 centimeters in size, and similar to a bullseye in appearance. Although the existence of photodistributed erythema multiforme has been recognized for years, few cases have been described to date.
Access a collection of canadian resources on all aspects of english and french, including quizzes. Granular c3 and igm at basement membrane and in vessels. In erythema multiforme minor, mucous membrane involvement is absent or mild. Please use one of the following formats to cite this article in your essay, paper or report. Eritema multiforme minor pdf republic of fenerbahce. The term erythema multiforme em includes a wide and controversial variety of clinical expressions at the present time.